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a good portion of the science work

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that's being done on the international

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space station is coming here through

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universities or government agencies but

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not all of it for instance there are

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drug companies that are using the

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weightless environment on the space

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station to improve their products my

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colleague lori meggs at the marshall

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space flight center in huntsville

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alabama recently spoke with a

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representative of eli lillian company

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which has been in business since 1876

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to find out how that company is

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utilizing the world's laboratory on

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orbit

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let's talk about eli lilly's involvement

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with the space station that's quite a

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combination yeah we've got four

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experiments going up at the end of 2015

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and into 2016.

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and they're really looking at very

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different things so we set out uh

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set ourselves up for a number of

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different experiments to learn different

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things and if something didn't work out

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that would be fine

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what are we looking at

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first experiment is looking at a

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investigated

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product we're looking at a new molecule

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that has some very interesting

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properties in

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a muscle wasting and it

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counters muscle wasting diseases so it's

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of interest to us and it's of interest

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to nasa

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the second

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experiment is looking at crystallization

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it's actually two sets of experiments

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the first is looking at co-crystallizing

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proteins of interest with molecules that

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we're working on to see how they fit

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together getting crystals of those and

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the other is looking at hard to

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crystallize proteins

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mostly self-surface proteins

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the third experiment is looking at

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freeze drying lawfulization sort the

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technical term

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but when you take a large batch of

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material and you freeze dry it it tends

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to layer out like a cake and those

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different layers represent different

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forms of the same material

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crystals or powders or

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and that's a bad thing for us because we

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want everything to be uniform especially

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if it's drug product so we want to

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understand where that layering is

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occurring is it happening when it

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freezes or is it happening when it gets

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dried

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so we're i'm actually going to make a

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big batch of material and we're going to

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freeze dry some of it on earth and then

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we're going to freeze dry some of it in

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space and then we're going to freeze

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some of it on earth and dry it in space

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and freeze some of it in space and dry

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it on earth

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and logistically that is the most

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difficult one because the last

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experiment where we freeze in space

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and then drop it out orbit and then

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bring it back we have to have a facility

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nearby that we can drive it to and dry

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it in while it's still frozen

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so wow so that's going to happen in san

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diego one of our sites in san diego

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and then the last experiment which was

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supposedly the easiest one to execute we

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thought

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the simplest is a mixing experiment

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we're taking a liquid a solid and a gas

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we're mixing them together

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when we take a mixture of material like

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that on earth

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we can watch how it dissolves and there

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tends to be an issue associated with how

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much material floats that has an impact

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on how well it dissolves or how fast it

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dissolves

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and that's called the float effect and

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we're trying to counter that by putting

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it in an environment where there is no

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float

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and see what the impact is

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that experiment we thought would be the

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easiest just mixing up a bunch of stuff

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but it is technically extremely

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challenging how do you measure it how do

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you get the liquid in there once

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everything else is in there how do you

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mix it consistently

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space isn't easy space is not easy no

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they're all designed to have some impact

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or lead to better understanding for us

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and how we do some of the things that

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you know are basic fundamental things

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that we do

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in our labs at the same time some of

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them are more specific to certain

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situations but again they're built to

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teach us something about

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what we think we know people who work at

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the company the people who are involved

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in a lot of these experiments or are

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scientists chemists biologists what have

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you

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but these efforts with nasa have really

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forced us to have conversations that

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many of us have not had since we were

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undergraduates you know about basic

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science or how we think things will

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happen

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and it's oftentimes

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the the most powerful experiments are

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the simple ones where you pretty much

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know what to expect and it doesn't

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happen that way right makes you